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Proteome-wide

Omni 1000

Delivering deep biological insight with absolute quantification across 1,000 judiciously selected proteins — balancing comprehensive pathway coverage, clinical relevance, and discovery-ready utility.

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Broad Coverage, Real-World Utility

92% Most Valuable Proteins

Percentage of most valuable proteins (MVPs) captured on Omni, curated from top literature, mid-plex panels, endpoint assays, and pharma-preferred pathways to maximize relevance for discovery and development.

100% Level 0 Reactome Coverage

Reflects the percentage of top-level biological systems captured on Omni, ensuring full representation across foundational cellular and physiological processes as defined by Reactome’s highest organizational tier.

84% Level 1 Reactome Coverage

Represents the proportion of detailed functional pathways covered within each top-level system. This metric captures the depth of Omni’s biological breadth, mapping into specific molecular cascades and processes across human biology.

100% MeSH Disease Classes

Tracks Omni’s ability to cover protein markers across all MeSH disease categories, ensuring broad utility for disease biology by aligning with the standard NIH classification of human health conditions.

100% KEGG Drug Discovery Pathways

Measures Omni’s coverage of the 46 most studied KEGG pathways, prioritized based on pharmaceutical pipeline activity, enabling high relevance to drug discovery and translational research across therapeutic areas.

95% Disease Prediction Power

Benchmarked against UK Biobank data, this metric reflects how much of the disease-predictive signal from a large 3,000-protein panel is retained by Omni’s overlapping 800-protein subset.

92%

of Most Valuable Proteins

100%

Level 0 Reactome Coverage

80%

Level 1 reactome coverage

100%

MSH Disease Classes

100%

KEGG Drug Discovery Pathways

95%

Disease Prediction Power

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How we selected the most informative 1000 proteins

The Omni 1000 panel was designed through a two-pronged strategy. We first curated the Most Valuable Proteins — well-established biomarkers with proven utility across drug discovery and translational research. Second, we used a data-driven approach — applying machine learning and optimization methods on public high-plex proteomic datasets. The result was 1000 proteins that maximize biological coverage and recapitulate patient phenotypic information, all while minimizing redundancy.

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Nomic Omni 1000 Target Library

Explore the list of Omni protein targets.

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Results 1

Sort by
Filtering by:
Tag
Operator
Value
Target Name
Uniprot ID
Gene Name
filter-tests
‍
IL21
Q9HBE4
IL21
3.2 Signal transduction
3.3 Signaling molecules and interaction
5.1 Immune system
6.6 Immune disease
Omni 1000
Core Immune
Flex
Immune System
Secreted
IL20RB
Q6UXL0
IL20RB
3.2 Signal transduction
3.3 Signaling molecules and interaction
Omni 1000
Flex
Immune System
Cell Membrane
IL20RA
Q9UHF4
IL20RA
3.2 Signal transduction
3.3 Signaling molecules and interaction
Omni 1000
Core Immune
Flex
Immune System
Cell Membrane
IL20
Q9NYY1
IL20
3.2 Signal transduction
3.3 Signaling molecules and interaction
Omni 1000
Core Immune
Flex
Immune System
Secreted
IL2
P60568
IL2
3.2 Signal transduction
3.3 Signaling molecules and interaction
5.1 Immune system
6.1 Cancer: overview
6.3 Infectious disease: viral
6.4 Infectious disease: bacterial
6.5 Infectious disease: parasitic
6.6 Immune disease
6.10 Endocrine and metabolic disease
Omni 1000
Core Immune
Flex
Gene expression (Transcription)
Immune System
Signal Transduction
Secreted
IL1RN
P18510
IL1RN
3.3 Signaling molecules and interaction
Omni 1000
Core Immune
Core CardioMet
Flex
Immune System
Secreted
Cytoplasm
IL1RL2
Q9HB29
IL1RL2
3.3 Signaling molecules and interaction
Omni 1000
Core Immune
Core CardioMet
Flex
Immune System
Cell Membrane
IL1RAP
Q9NPH3
IL1RAP
3.2 Signal transduction
3.3 Signaling molecules and interaction
5.1 Immune system
5.7 Sensory system
Omni 1000
Core Immune
Flex
No items found.
Secreted
Cell Membrane
IL1R2
P27930
IL1R2
3.3 Signaling molecules and interaction
5.1 Immune system
6.1 Cancer: overview
6.2 Cancer: specific types
6.3 Infectious disease: viral
6.5 Infectious disease: parasitic
6.9 Cardiovascular disease
Omni 1000
Core Immune
Core CardioMet
Flex
Immune System
Secreted
Cell Membrane
IL1R1
P14778
IL1R1
3.2 Signal transduction
3.3 Signaling molecules and interaction
5.1 Immune system
5.7 Sensory system
5.8 Development and regeneration
6.3 Infectious disease: viral
6.4 Infectious disease: bacterial
6.5 Infectious disease: parasitic
6.9 Cardiovascular disease
Omni 1000
Core Immune
Core CardioMet
Flex
Disease
Immune System
Secreted
Cell Membrane
IL1B
P01584
IL1B
3.2 Signal transduction
3.3 Signaling molecules and interaction
4.2 Cell growth and death
5.1 Immune system
5.7 Sensory system
5.8 Development and regeneration
6.3 Infectious disease: viral
6.4 Infectious disease: bacterial
6.5 Infectious disease: parasitic
6.6 Immune disease
6.7 Neurodegenerative disease
6.9 Cardiovascular disease
6.10 Endocrine and metabolic disease
6.12 Drug resistance: antineoplastic
Omni 1000
Core Immune
Core CardioMet
Flex
Disease
Immune System
Programmed Cell Death
Secreted
Cytoplasm
IL1A
P01583
IL1A
3.2 Signal transduction
3.3 Signaling molecules and interaction
4.2 Cell growth and death
5.1 Immune system
5.8 Development and regeneration
6.3 Infectious disease: viral
6.4 Infectious disease: bacterial
6.5 Infectious disease: parasitic
6.6 Immune disease
6.7 Neurodegenerative disease
6.9 Cardiovascular disease
6.10 Endocrine and metabolic disease
Omni 1000
Core Immune
Core CardioMet
Flex
Cellular responses to stimuli
Disease
Immune System
Programmed Cell Death
Secreted
Nucleus
Cytoplasm
IL18R1
Q13478
IL18R1
3.2 Signal transduction
3.3 Signaling molecules and interaction
6.6 Immune disease
Omni 1000
Core Immune
Flex
Immune System
Cell Membrane
IL18BP
O95998
IL18BP
No items found.
Omni 1000
Flex
Immune System
Secreted
IL18
Q14116
IL18
3.3 Signaling molecules and interaction
5.1 Immune system
6.3 Infectious disease: viral
6.4 Infectious disease: bacterial
6.5 Infectious disease: parasitic
6.6 Immune disease
6.9 Cardiovascular disease
Omni 1000
Core Immune
Core CardioMet
Flex
Disease
Immune System
Programmed Cell Death
Secreted
Cytoplasm
IL17RB
Q9NRM6
IL17RB
3.3 Signaling molecules and interaction
5.1 Immune system
Omni 1000
Core Immune
Flex
Immune System
Secreted
Cell Membrane
IL17RA
Q96F46
IL17RA
3.3 Signaling molecules and interaction
5.1 Immune system
6.10 Endocrine and metabolic disease
Omni 1000
Core Immune
Core CardioMet
Flex
Disease
Immune System
Secreted
Cell Membrane
IL17F
Q96PD4
IL17F
3.3 Signaling molecules and interaction
5.1 Immune system
6.6 Immune disease
Omni 1000
Core Immune
Flex
Disease
Immune System
Secreted
IL17D
Q8TAD2
IL17D
3.3 Signaling molecules and interaction
5.1 Immune system
Omni 1000
Core Immune
Flex
No items found.
Secreted
IL17C
Q9P0M4
IL17C
3.3 Signaling molecules and interaction
5.1 Immune system
Omni 1000
Core Immune
Flex
Immune System
Secreted
IL17B
Q9UHF5
IL17B
3.3 Signaling molecules and interaction
5.1 Immune system
Omni 1000
Core Immune
Flex
No items found.
Secreted
IL17A
Q16552
IL17A
3.3 Signaling molecules and interaction
5.1 Immune system
6.6 Immune disease
6.10 Endocrine and metabolic disease
Omni 1000
Core Immune
Flex
Disease
Immune System
Secreted
IL16
Q14005
IL16
3.3 Signaling molecules and interaction
Omni 1000
Core Immune
Flex
Immune System
Secreted
Nucleus
Cytoplasm
IL15;IL15RA
P40933;Q13261
IL15;IL15RA
3.2 Signal transduction
3.3 Signaling molecules and interaction
5.1 Immune system
6.1 Cancer: overview
6.3 Infectious disease: viral
6.6 Immune disease
Omni 1000
Flex
Immune System
Secreted
IL15
P40933
IL15
3.2 Signal transduction
3.3 Signaling molecules and interaction
5.1 Immune system
6.1 Cancer: overview
6.3 Infectious disease: viral
6.6 Immune disease
Omni 1000
Core Immune
Flex
Immune System
Secreted
Nucleus
Cytoplasm
IL13RA1
P78552
IL13RA1
3.2 Signal transduction
3.3 Signaling molecules and interaction
6.1 Cancer: overview
Omni 1000
Flex
Immune System
Cell Membrane
IL13
P35225
IL13
3.2 Signal transduction
3.3 Signaling molecules and interaction
5.1 Immune system
6.1 Cancer: overview
6.6 Immune disease
Omni 1000
Core Immune
Flex
Immune System
Secreted
IL12RB2
Q99665
IL12RB2
3.2 Signal transduction
3.3 Signaling molecules and interaction
5.1 Immune system
6.1 Cancer: overview
6.6 Immune disease
Omni 1000
Core Immune
Flex
Immune System
Cell Membrane
IL12RB1
P42701
IL12RB1
3.2 Signal transduction
3.3 Signaling molecules and interaction
5.1 Immune system
6.1 Cancer: overview
6.6 Immune disease
Omni 1000
Core Immune
Flex
Immune System
Cell Membrane
IL11
P20809
IL11
3.2 Signal transduction
3.3 Signaling molecules and interaction
5.1 Immune system
6.6 Immune disease
Omni 1000
Core Immune
Flex
Immune System
Secreted
IL10RB
Q08334
IL10RB
3.2 Signal transduction
3.3 Signaling molecules and interaction
6.3 Infectious disease: viral
6.4 Infectious disease: bacterial
6.5 Infectious disease: parasitic
Omni 1000
Core Immune
Flex
Immune System
Cell Membrane
IL10RA
Q13651
IL10RA
3.2 Signal transduction
3.3 Signaling molecules and interaction
6.3 Infectious disease: viral
6.4 Infectious disease: bacterial
6.5 Infectious disease: parasitic
Omni 1000
Core Immune
Flex
Disease
Immune System
Cell Membrane
Cytoplasm
IL10
P22301
IL10
3.2 Signal transduction
3.3 Signaling molecules and interaction
4.1 Transport and catabolism
5.1 Immune system
6.4 Infectious disease: bacterial
6.5 Infectious disease: parasitic
6.6 Immune disease
Omni 1000
Core Immune
Core CardioMet
Flex
Disease
Immune System
Secreted
IGSF11
Q5DX21
IGSF11
3.3 Signaling molecules and interaction
Omni 1000
Flex
No items found.
Cell Membrane
IGHG4
P01861
IGHG4
No items found.
Omni 1000
Flex
Disease
Immune System
Secreted
Cell Membrane
IGHE
P01854
IGHE
No items found.
Omni 1000
Flex
Immune System
Secreted
Cell Membrane
IGFBP6
P24592
IGFBP6
No items found.
Omni 1000
Core CardioMet
Flex
Metabolism of proteins
Secreted
IGFBP4
P22692
IGFBP4
No items found.
Omni 1000
Core CardioMet
Flex
Metabolism of proteins
Secreted
IGFBP3
P17936
IGFBP3
4.2 Cell growth and death
5.2 Endocrine system
6.1 Cancer: overview
Omni 1000
Core CardioMet
Flex
Gene expression (Transcription)
Metabolism of proteins
Secreted
Nucleus
IGFBP2
P18065
IGFBP2
No items found.
Omni 1000
Core CardioMet
Flex
Metabolism of proteins
Secreted
IGFBP1
P08833
IGFBP1
No items found.
Omni 1000
Core CardioMet
Flex
Cellular responses to stimuli
Gene expression (Transcription)
Metabolism of proteins
Secreted
IGF2R
P11717
IGF2R
2.6 Information processing in viruses
4.1 Transport and catabolism
Omni 1000
Flex
Immune System
Vesicle-mediated transport
Cell Membrane
Cytoplasm
IGF1R
P08069
IGF1R
3.2 Signal transduction
4.1 Transport and catabolism
4.2 Cell growth and death
4.3 Cellular community - eukaryotes
5.2 Endocrine system
5.6 Nervous system
5.9 Aging
6.1 Cancer: overview
6.2 Cancer: specific types
6.12 Drug resistance: antineoplastic
Omni 1000
Flex
Disease
Signal Transduction
Cell Membrane
IGF1
P05019
IGF1
3.2 Signal transduction
4.2 Cell growth and death
4.3 Cellular community - eukaryotes
5.2 Endocrine system
5.5 Excretory system
5.6 Nervous system
5.7 Sensory system
5.9 Aging
6.1 Cancer: overview
6.2 Cancer: specific types
6.9 Cardiovascular disease
6.12 Drug resistance: antineoplastic
Omni 1000
Core CardioMet
Flex
Hemostasis
Metabolism of proteins
Signal Transduction
Secreted
IFNW1
P05000
IFNW1
3.2 Signal transduction
3.3 Signaling molecules and interaction
5.1 Immune system
Omni 1000
Flex
No items found.
Secreted
IFNLR1
Q8IU57
IFNLR1
3.2 Signal transduction
3.3 Signaling molecules and interaction
Omni 1000
Flex
Immune System
Cell Membrane
IFNL3
Q8IZI9
IFNL3
3.2 Signal transduction
3.3 Signaling molecules and interaction
Omni 1000
Flex
Immune System
Secreted
IFNL2
Q8IZJ0
IFNL2
3.2 Signal transduction
3.3 Signaling molecules and interaction
Omni 1000
Core Immune
Flex
Immune System
Secreted
IFNL1
Q8IU54
IFNL1
3.2 Signal transduction
3.3 Signaling molecules and interaction
Omni 1000
Core Immune
Flex
Immune System
Secreted
IFNGR1
P15260
IFNGR1
3.2 Signal transduction
3.3 Signaling molecules and interaction
4.2 Cell growth and death
5.1 Immune system
5.8 Development and regeneration
6.1 Cancer: overview
6.3 Infectious disease: viral
6.4 Infectious disease: bacterial
6.5 Infectious disease: parasitic
6.6 Immune disease
Omni 1000
Core Immune
Flex
Disease
Immune System
Cell Membrane
IFNG
P01579
IFNG
2.3 Folding, sorting and degradation
3.2 Signal transduction
3.3 Signaling molecules and interaction
4.2 Cell growth and death
5.1 Immune system
5.8 Development and regeneration
6.1 Cancer: overview
6.3 Infectious disease: viral
6.4 Infectious disease: bacterial
6.5 Infectious disease: parasitic
6.6 Immune disease
6.9 Cardiovascular disease
6.10 Endocrine and metabolic disease
Omni 1000
Core Immune
Core CardioMet
Flex
Gene expression (Transcription)
Immune System
Secreted
IFNE
Q86WN2
IFNE
3.2 Signal transduction
3.3 Signaling molecules and interaction
5.1 Immune system
Omni 1000
Flex
No items found.
Secreted
IFNB1
P01574
IFNB1
3.2 Signal transduction
3.3 Signaling molecules and interaction
4.2 Cell growth and death
5.1 Immune system
5.8 Development and regeneration
6.3 Infectious disease: viral
6.4 Infectious disease: bacterial
6.5 Infectious disease: parasitic
6.9 Cardiovascular disease
6.10 Endocrine and metabolic disease
Omni 1000
Core Immune
Flex
Cellular responses to stimuli
Disease
Hemostasis
Immune System
Secreted
IFNAR2
P48551
IFNAR2
3.2 Signal transduction
3.3 Signaling molecules and interaction
4.2 Cell growth and death
5.1 Immune system
5.8 Development and regeneration
6.1 Cancer: overview
6.3 Infectious disease: viral
Omni 1000
Flex
No items found.
Secreted
Cell Membrane
IFNAR1
P17181
IFNAR1
3.2 Signal transduction
3.3 Signaling molecules and interaction
4.2 Cell growth and death
5.1 Immune system
5.8 Development and regeneration
6.1 Cancer: overview
6.3 Infectious disease: viral
Omni 1000
Flex
Disease
Immune System
Cell Membrane
Cytoplasm
IFNA2
P01563
IFNA2
3.2 Signal transduction
3.3 Signaling molecules and interaction
4.2 Cell growth and death
5.1 Immune system
6.1 Cancer: overview
6.3 Infectious disease: viral
6.4 Infectious disease: bacterial
6.6 Immune disease
6.9 Cardiovascular disease
6.10 Endocrine and metabolic disease
Omni 1000
Core Immune
Flex
Disease
Hemostasis
Immune System
Secreted
IDUA
P35475
IDUA
1.0 Global and overview maps
1.7 Glycan biosynthesis and metabolism
4.1 Transport and catabolism
Omni 1000
Core CardioMet
Flex
Disease
Metabolism
Cytoplasm
IDS
P22304
IDS
1.0 Global and overview maps
1.7 Glycan biosynthesis and metabolism
4.1 Transport and catabolism
Omni 1000
Core CardioMet
Flex
Disease
Metabolism
Cytoplasm
IDO2
Q6ZQW0
IDO2
1.0 Global and overview maps
1.5 Amino acid metabolism
6.5 Infectious disease: parasitic
Omni 1000
Flex
Metabolism
Cytoplasm
IDO1
P14902
IDO1
1.0 Global and overview maps
1.5 Amino acid metabolism
6.5 Infectious disease: parasitic
Omni 1000
Flex
Metabolism
Cytoplasm
IDH1
O75874
IDH1
1.0 Global and overview maps
1.1 Carbohydrate metabolism
1.6 Metabolism of other amino acids
4.1 Transport and catabolism
6.1 Cancer: overview
Omni 1000
Flex
Cellular responses to stimuli
Disease
Immune System
Metabolism
Protein localization
Cytoplasm
ICOSLG
O75144
ICOSLG
3.3 Signaling molecules and interaction
5.1 Immune system
Omni 1000
Core Immune
Flex
Immune System
Cell Membrane
ICAM5
Q9UMF0
ICAM5
No items found.
Omni 1000
Flex
Extracellular matrix organization
Immune System
Cell Membrane
ICAM4
Q14773
ICAM4
No items found.
Omni 1000
Flex
Extracellular matrix organization
Immune System
Secreted
Cell Membrane
ICAM3
P32942
ICAM3
3.3 Signaling molecules and interaction
Omni 1000
Flex
Extracellular matrix organization
Immune System
Cell Membrane
ICAM2
P13598
ICAM2
3.3 Signaling molecules and interaction
5.1 Immune system
Omni 1000
Core Immune
Core CardioMet
Flex
Extracellular matrix organization
Immune System
Cell Membrane
ICAM1
P05362
ICAM1
3.2 Signal transduction
3.3 Signaling molecules and interaction
5.1 Immune system
6.3 Infectious disease: viral
6.4 Infectious disease: bacterial
6.5 Infectious disease: parasitic
6.6 Immune disease
6.9 Cardiovascular disease
6.10 Endocrine and metabolic disease
Omni 1000
Core Immune
Core CardioMet
Flex
Extracellular matrix organization
Immune System
Cell Membrane
HTR2A
P28223
HTR2A
3.2 Signal transduction
3.3 Signaling molecules and interaction
4.3 Cellular community - eukaryotes
5.6 Nervous system
5.7 Sensory system
Omni 1000
Flex
Signal Transduction
Cell Membrane
Cytoplasm
HSPG2
P98160
HSPG2
2.6 Information processing in viruses
3.3 Signaling molecules and interaction
4.5 Cell motility
6.1 Cancer: overview
6.3 Infectious disease: viral
Omni 1000
Core CardioMet
Flex
Disease
Extracellular matrix organization
Metabolism
Metabolism of proteins
Sensory Perception
Secreted
HSPD1
P10809
HSPD1
2.3 Folding, sorting and degradation
6.4 Infectious disease: bacterial
6.9 Cardiovascular disease
6.10 Endocrine and metabolic disease
Omni 1000
Flex
Gene expression (Transcription)
Metabolism of proteins
Protein localization
Cytoplasm
HSPB1
P04792
HSPB1
3.2 Signal transduction
6.5 Infectious disease: parasitic
Omni 1000
Core CardioMet
Flex
Metabolism of RNA
Signal Transduction
Nucleus
Cytoplasm
HSPA8
P11142
HSPA8
2.1 Transcription
2.3 Folding, sorting and degradation
3.2 Signal transduction
4.1 Transport and catabolism
5.1 Immune system
5.2 Endocrine system
5.9 Aging
6.3 Infectious disease: viral
6.4 Infectious disease: bacterial
6.5 Infectious disease: parasitic
6.7 Neurodegenerative disease
6.9 Cardiovascular disease
Omni 1000
Flex
Autophagy
Cellular responses to stimuli
Developmental Biology
Disease
Immune System
Metabolism of RNA
Metabolism of proteins
Neuronal System
Vesicle-mediated transport
Cell Membrane
Nucleus
Cytoplasm
HSP90AA1
P07900
HSP90AA1
2.3 Folding, sorting and degradation
3.2 Signal transduction
4.2 Cell growth and death
5.1 Immune system
5.2 Endocrine system
6.1 Cancer: overview
6.2 Cancer: specific types
6.4 Infectious disease: bacterial
6.9 Cardiovascular disease
Omni 1000
Flex
Autophagy
Cell Cycle
Cellular responses to stimuli
Developmental Biology
Disease
Gene expression (Transcription)
Immune System
Metabolism
Organelle biogenesis and maintenance
Programmed Cell Death
Signal Transduction
Vesicle-mediated transport
Cell Membrane
Nucleus
Cytoplasm
HS3ST4
Q9Y661
HS3ST4
No items found.
Omni 1000
Flex
Metabolism
Cytoplasm
HRG
P04196
HRG
No items found.
Omni 1000
Flex
Hemostasis
Secreted
HPSE
Q9Y251
HPSE
1.0 Global and overview maps
1.7 Glycan biosynthesis and metabolism
6.1 Cancer: overview
Omni 1000
Flex
Immune System
Metabolism
Secreted
Cell Membrane
Nucleus
Cytoplasm
HPGDS
O60760
HPGDS
1.0 Global and overview maps
1.3 Lipid metabolism
1.6 Metabolism of other amino acids
1.11 Xenobiotics biodegradation and metabolism
6.1 Cancer: overview
Omni 1000
Flex
Metabolism
Cytoplasm
HP
P00738
HP
No items found.
Omni 1000
Flex
Immune System
Vesicle-mediated transport
Secreted
HNRNPK
P61978
HNRNPK
2.1 Transcription
6.1 Cancer: overview
Omni 1000
Flex
Disease
Metabolism of RNA
Metabolism of proteins
Nucleus
Cytoplasm
HMOX2
P30519
HMOX2
1.0 Global and overview maps
1.8 Metabolism of cofactors and vitamins
5.4 Digestive system
Omni 1000
Flex
Cellular responses to stimuli
Immune System
Metabolism
Signal Transduction
Transport of small molecules
Cytoplasm
HMOX1
P09601
HMOX1
1.0 Global and overview maps
1.8 Metabolism of cofactors and vitamins
3.2 Signal transduction
4.2 Cell growth and death
5.4 Digestive system
6.1 Cancer: overview
6.2 Cancer: specific types
6.9 Cardiovascular disease
Omni 1000
Core Immune
Core CardioMet
Flex
Cellular responses to stimuli
Disease
Immune System
Metabolism
Protein localization
Transport of small molecules
Cytoplasm
HMGN1
P05114
HMGN1
No items found.
Omni 1000
Flex
No items found.
Nucleus
Cytoplasm
HJV
Q6ZVN8
HJV
3.2 Signal transduction
Omni 1000
Flex
Developmental Biology
Secreted
Cell Membrane
HIF1A
Q16665
HIF1A
3.2 Signal transduction
4.1 Transport and catabolism
5.1 Immune system
5.2 Endocrine system
6.1 Cancer: overview
6.2 Cancer: specific types
6.3 Infectious disease: viral
Omni 1000
Flex
Cellular responses to stimuli
Circadian Clock
Immune System
Metabolism of proteins
Signal Transduction
Nucleus
Cytoplasm
HHLA2
Q9UM44
HHLA2
No items found.
Omni 1000
Flex
No items found.
Cell Membrane
HGF
P14210
HGF
3.2 Signal transduction
4.3 Cellular community - eukaryotes
6.1 Cancer: overview
6.2 Cancer: specific types
6.5 Infectious disease: parasitic
6.12 Drug resistance: antineoplastic
Omni 1000
Core CardioMet
Flex
Disease
Hemostasis
Immune System
Signal Transduction
Secreted
HDAC1
Q13547
HDAC1
2.5 Chromosome
3.2 Signal transduction
4.2 Cell growth and death
5.1 Immune system
5.2 Endocrine system
5.9 Aging
6.1 Cancer: overview
6.2 Cancer: specific types
6.3 Infectious disease: viral
6.7 Neurodegenerative disease
6.8 Substance dependence
Omni 1000
Flex
Cell Cycle
Chromatin organization
Developmental Biology
Disease
Gene expression (Transcription)
Hemostasis
Metabolism of proteins
Signal Transduction
Nucleus
HBEGF
Q99075
HBEGF
3.2 Signal transduction
5.2 Endocrine system
6.1 Cancer: overview
6.2 Cancer: specific types
6.3 Infectious disease: viral
6.4 Infectious disease: bacterial
6.12 Drug resistance: antineoplastic
Omni 1000
Core CardioMet
Flex
Disease
Signal Transduction
Vesicle-mediated transport
Secreted
Cell Membrane
HAO1
Q9UJM8
HAO1
1.0 Global and overview maps
1.1 Carbohydrate metabolism
4.1 Transport and catabolism
Omni 1000
Core CardioMet
Flex
Metabolism
Protein localization
Cytoplasm
GZMK
P49863
GZMK
No items found.
Omni 1000
Flex
No items found.
Secreted
Cell Membrane
Cytoplasm
GZMH
P20718
GZMH
No items found.
Omni 1000
Flex
Metabolism of proteins
Cytoplasm
GZMB
P10144
GZMB
4.2 Cell growth and death
5.1 Immune system
6.1 Cancer: overview
6.6 Immune disease
6.10 Endocrine and metabolic disease
Omni 1000
Core Immune
Flex
Disease
Programmed Cell Death
Signal Transduction
Secreted
Cytoplasm
GZMA
P12544
GZMA
3.3 Signaling molecules and interaction
Omni 1000
Core Immune
Flex
No items found.
Secreted
Cytoplasm
GSTP1
P09211
GSTP1
1.0 Global and overview maps
1.6 Metabolism of other amino acids
1.11 Xenobiotics biodegradation and metabolism
6.1 Cancer: overview
6.2 Cancer: specific types
6.9 Cardiovascular disease
6.12 Drug resistance: antineoplastic
Omni 1000
Flex
Cellular responses to stimuli
Drug ADME
Immune System
Metabolism
Nucleus
Cytoplasm
GSN
P06396
GSN
4.5 Cell motility
5.1 Immune system
6.1 Cancer: overview
Omni 1000
Core Immune
Flex
Immune System
Metabolism of proteins
Programmed Cell Death
Sensory Perception
Secreted
Cytoplasm
GRN
P28799
GRN
No items found.
Omni 1000
Core CardioMet
Flex
Immune System
Secreted
Cytoplasm
GRIA2
P42262
GRIA2
3.2 Signal transduction
3.3 Signaling molecules and interaction
5.6 Nervous system
5.10 Environmental adaptation
6.7 Neurodegenerative disease
6.8 Substance dependence
Omni 1000
Flex
Gene expression (Transcription)
Neuronal System
Cell Membrane
GREM1
O60565
GREM1
3.2 Signal transduction
Omni 1000
Flex
Developmental Biology
Secreted
GRB2
P62993
GRB2
3.2 Signal transduction
4.3 Cellular community - eukaryotes
5.1 Immune system
5.2 Endocrine system
5.6 Nervous system
5.8 Development and regeneration
5.10 Environmental adaptation
6.1 Cancer: overview
6.2 Cancer: specific types
6.3 Infectious disease: viral
6.8 Substance dependence
6.12 Drug resistance: antineoplastic
Omni 1000
Flex
Disease
Immune System
Signal Transduction
Nucleus
Cytoplasm
GPX4
P36969
GPX4
1.0 Global and overview maps
1.3 Lipid metabolism
1.6 Metabolism of other amino acids
4.2 Cell growth and death
Omni 1000
Flex
Metabolism
Cytoplasm
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WHITE PAPER

Omni 1000: Biological Intelligence Delivered at Scale

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Resources

All Resources
News
•
October 6, 2026

Nomic’s Proteomics Platform to Power VO Health’s Molecular Fitness Insights

VO Health’s Molecular Fitness Blood Test™ will utilize deep protein profiling to estimate VO₂ Max and characterize the biological pathways underlying cardiorespiratory fitness and performance
Read more
Dataset
•

Perturb PBMC

Functional Proteomics of the PBMC Secretome
Read more
Application Note
•
August 16, 2026

Proteomics for Drug Safety Assessment

Detect toxicity before candidates advance. This application note shows how high-throughput proteomic profiling can reveal toxicity signals while helping resolve the mechanisms behind them.
Read more
On Demand
•
July 16, 2026

Interpreting CRISPR Screens Through Protein-Level Biology

Amanda McQuade and Nathaniel Robichaud discuss how integrated proteomic and transcriptomic profiling can reveal cellular responses to genetic perturbations that are not captured through RNA analysis alone.
Read more
News
•
June 25, 2026

Nomic joins the HESI Global OASIS Consortium to Advance Human-Relevant Safety Assessment Through Proteomics

Study will profile over 3,000 human liver-derived samples to generate proteomic training datasets for New Approach Methodologies and AI-enabled toxicity prediction
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News
•
June 16, 2026

Nomic and Wellcome Sanger Institute Collaborate to Bring Protein-Level Resolution to the Genetics of Immune Diversity

High-plex protein profiling across 1,500+ perturbed PBMC samples enables functional mapping of immune genetics across diverse Latin American cohorts
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News
•
April 20, 2026

Nomic and Broad Clinical Labs Partner to Integrate Omni 1000 into Discovery and Translational Workflows

Nomic and Broad Clinical Labs partner to unlock broader applications for proteomics through high-plex, quantitative data that enables cross-study comparable insights.
Read more
Application Note
•
April 19, 2026

Proteomics: Stop inferring biology, start measuring it

Discover how scalable, quantitative proteomics bridges drug development from discovery screens to clinical translation
Read more
White Paper
Nomic Bio
•
April 18, 2026

Omni 1000: Biological Intelligence Delivered at Scale

Proteomics has long required compromise: breadth versus cost, absolute quantification versus depth, scalability versus insight. Omni 1000 eliminates those constraints, delivering 1063 rigorously selected proteins in a single quantitative assay, yielding data that is interoperable across studies.
Read more
On Demand
•
March 19, 2026

Video: Perturb PBMC - Functional Proteomics of the PBMC Secretome

Hosted by Nathaniel Robichaud, PhD, Partnerships Lead at Nomic, this video explores findings from our large-scale PBMC screen and their implications for multiple sclerosis.
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News
•
November 11, 2025

Perturb-PBMC: Functional Proteomics of the PBMC Secretome

Read more
News
•
November 7, 2025

Nomic Publishes Foundational Protein Quantification Technology in Nature Methods

The company highlights how its technology powers large-scale proteomic perturbation studies, unveiling Perturb-PBMC, a 1.4 million–protein PBMC dataset available in the Nomic Portal.
Read more
On Demand
•
October 17, 2025

Watch: Currents of Pan-Cancer - Insights from 1,000 Circulating Proteins

In this webinar Lloyd Bod, PhD and Nathaniel Robichaud, PhD, will discuss how large-scale profiling of the circulating proteome across multiple cancer types reveals unique tumor-specific protein signatures and provides new insights into treatment response.
Read more
News
•
September 4, 2025

Nomic Bio Awards Omni 1000 Proteomics Grants to Seven Institutions, Enabling 5 Million Data Points Across 5,000 Samples

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Technical note
•
July 22, 2025

Nomic Platform Validation Methods and Results

Nomic’s nELISA® technology is a versatile, proteome-wide multiplexed solution designed for scalable, high-throughput protein quantification. At its core is a library of 1,000 expertly curated assays developed to support drug development and biomarker discovery.
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Brochure
Nomic Bio
•
May 30, 2025

Protein Profiling Brochure

Proteomics without Compromise
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News
•
May 13, 2025

Omni 1000 Grant Opportunity in High Plex Proteomics

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News
•
May 13, 2025

Nomic Bio Debuts $50 Proteome with Absolute Quantification Through Launch of Omni 1000

For the first time, researchers can access a quantitative proteome-wide solution that profiles 1000 of the most informative proteins at high-throughput.
Read more
On Demand
•
May 13, 2025

Watch: 1000 Proteins to Unlock the Proteome

1000 Proteins to Unlock the Proteome: Delivering Affordable, Scalable, and Quantitative Proteomics.
Read more
Technical note
Nomic Bio
•
November 1, 2024

The nELISA: A Massively Multiplexed & Miniaturized Immunoassay Platform for High-Throughput Protein Profiling

How nELISA miniaturizes immunoassays on beads, overcoming reagent-driven cross-reactivity and reducing costs.
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Publication
Milad Dagher & David Juncker
•
April 18, 2023

nELISA: A high-throughput, high-plex platform enables quantitative profiling of the secretome

BioRxiv ; We present the nELISA, a miniaturised, high-throughput, and high-fidelity protein profiling platform.
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White Paper
Nomic Bio
•
October 16, 2024

True Multiplexing with the nELISA

True Multiplexing Unlocks Scalable Proteomics
Read more
Technical note
Nomic Bio
•
January 14, 2025

Using the nELISA™ to Map Cytokine Interactions in a 10,000-well PBMC Perturbation Screen

High-throughput protein profiling technology enables comprehensive and quantitative mapping of cytokine interactions
Read more
News
Nomic Bio
•
September 24, 2024

Nomic® and Parker Institute for Cancer Immunotherapy (PICI) Launch Large-Scale Protein Profiling to Investigate Immunotherapy Responses in RADIOHEAD Study

Project will quantify circulating protein markers in ~3000 patient blood samples from PICI’s RADIOHEAD study using Nomic’s nELISA™ high-throughput protein profiling platform to better understand how patients respond to treatment
Read more
News
Nomic Bio
•
December 8, 2021

Nomic Closes $17 Million Series A to Develop and Commercialize the World’s Highest Throughput Proteomic Platform

Nomic is closing of an oversubscribed US$17 million Series A funding round, bringing the company's total funding to date to over US$21 million.
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News
Nomic Bio
•
June 28, 2023

Nomic Bio Appoints Byron Hewett to its Board of Directors

Hewett brings invaluable operational and strategic expertise to guide Nomic Bio through its crucial years of growth.
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News
Nomic Bio
•
December 8, 2021

Nomic to Provide nELISA to JUMP Cell Painting Consortium to Measure Protein Secretome for Phenotypic Drug Discovery

Nomic’s nELISA will be used to profile 200 secreted proteins for ten thousand samples to provide consortium partners complementary information about the secretome
Read more
Brochure
Nomic Bio
•
January 13, 2025

How To Access the nELISA Service

Accessing our profiling service is a simple and seamless experience. We offer comprehensive, end-to-end support to help you harness the power of the proteome.
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News
Nomic Bio
•
September 17, 2024

Nomic® Secures $42M in Oversubscribed Series B to Expand Access to Protein Profiling

The fresh capital will enable Nomic to accelerate the expansion of its commercial operations, further invest in advancing its state-of-the-art protein profiling platform, and broaden its transformative offerings to meet growing demand.
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News
MIlad Dagher, CEO
•
January 3, 2025

Bridging the Gaps in Proteomics

Enabling well-powered studies, absolute quantification, and unlimited content flexibility
Read more
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